Welcome to the Galvan Lab
Identifying molecular and biochemical alterations that cause Alzheimer's disease and other dementias
We seek to understand the processes that drive Alzheimer's disease (AD) with a focus on those that link aging to AD and other dementias, and to define the therapeutic potential of drug candidate molecules in AD.
We use advanced genetic manipulations in rodents, in vivo optical and MRI- and PET-based brain imaging, laser Doppler-based cerebral blood flow measures, primary cell culture systems and biochemical, cellular and molecular biology approaches, together with whole tissue and single-cell -omic and behavioral tools.
Our goal is to advance our understanding of age-associated neurological disease mechanisms and identify interventions to prevent or treat AD and other age-associated dementias.
Brain vascular endothelial cell senescence in Alzheimer's disease
Vascular tau in Alzheimer's and other tauopathies
Department of Biochemistry and Molecular Biology
Center for Geroscience and Healthy Brain Aging
University of Oklahoma Health Sciences Center
940 Stanton L. Young Blvd., BMSB 853
Oklahoma City, OK 73104
Phone: (405) 271-2227